In-depth: Monodisperse microbubbles
“The next generation of ultrasound contrast agents” Tide Micro
Our Microfluidic technology
We use flow focussing techniques for the production of microparticles. This technique uses the outer fluid, or continuous phase, and the geometry of the microfluidic chip to confine the inner fluid, or disperse phase. As the fluids flow through the junction the disperse phase is confined and focussed creating a point where it will break-up into small droplets or bubbles of uniform size. A schematic of this geometry can be seen on the left.
The applications that this geometry allows are diverse, with gas/liquid mixtures microbubbles can be created and liquid/liquid mixtures allow microdropletes to be created. It is even possible to create solid microparticles either through chemical reactions or post production treatments such as UV exposure. Using this geometry for large volume production means that uniform dispersions and emulsions can be made and slight modifications to the design can allow double emulsions or Janus droplets, those with a two component core, to be created.